Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29053198 | 1.00 | CHRNB2 (0.40) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL28458633 | 0.85 | CHRNB2 (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3ALOX15 | |
| SCHEMBL29991123 | 0.83 | ALDH1A1 (0.41) | LMNAALDH1A1KDM5AKDM4AKDM4C | |
| SCHEMBL30185810 | 0.82 | ALDH1A1 (0.55) | LMNAALDH1A1TSHRDNM1KDM5A | |
| SCHEMBL19852484 | 0.82 | ALDH1A1 (0.55) | LMNAALDH1A1TSHRDNM1KDM5A | |
| SCHEMBL499415 | 0.80 | ALDH1A1 (0.52) | CHRNB2CHRNA4CHRNB4LMNAALDH1A1 | |
| SCHEMBL22205611 | 0.77 | LMNA (0.44) | CHRNB2CHRNA4CHRNB4LMNAALDH1A1 | |
| SCHEMBL1667458 | 0.76 | ALDH1A1 (0.50) | ALOX15ALDH1A1TSHRDNM1KDM5A | |
| SCHEMBL2304549 | 0.76 | ALDH1A1 (0.50) | ALOX15ALDH1A1TSHRDNM1KDM5A | |
| SCHEMBL8142273 | 0.76 | ALDH1A1 (0.50) | ALOX15ALDH1A1TSHRDNM1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593238-B | Lysine-specific chemoenzymatic protein modification using microbial transglutaminase | 诺华股份有限公司 | 2020-09-08 | — | — | CN | disclosed |