Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CCR9 | P51686 | 1/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17737478 | 0.89 | ALDH1A1 (0.52) | ALDH1A1CCR9SLC40A1CCR2HTR1A | |
| SCHEMBL17737476 | 0.84 | ALOX12 (0.62) | ALDH1A1CCR9SLC40A1HTR1AHTR2A | |
| SCHEMBL17737362 | 0.76 | IDO1 (0.62) | ALDH1A1CCR9SLC40A1HTR1AHTR2A | |
| SCHEMBL17737480 | 0.75 | FFAR4 (0.46) | ALDH1A1CCR9SLC40A1CCR2HTR2A | |
| Hydrochloric Acid SCHEMBL20856389 | 0.72 | KDM4E (0.40) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL17737617 | 0.70 | RECQL (0.69) | ALDH1A1SLC40A1ALOX12MEN1KMT2A | |
| SCHEMBL3065621 | 0.70 | CES1 (0.55) | ALDH1A1HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL5899919 | 0.70 | MCL1 (0.69) | ALDH1A1CCR2CYP19A1CES1 | |
| SCHEMBL17737677 | 0.69 | RECQL (0.58) | ALDH1A1SLC40A1HTR1AHTR2AHTR7 | |
| SCHEMBL3064389 | 0.69 | CES1 (0.54) | ALDH1A1CYP19A1MEN1KMT2ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037553-A1 | INHIBITORS OF TRYPTOPHAN-2,3-DIOXYGENASE OR INDOLEAMINE-2,3-DIOXYGENASE | IOMET PHARMA LTD. (GB) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037553-A1 | INHIBITORS OF TRYPTOPHAN-2,3-DIOXYGENASE OR INDOLEAMINE-2,3-DIOXYGENASE | TDO2, IDO2, IDO1 | ALDH1A1 3640/4885CCR9 1656/4885SLC40A1 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.