Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918077 | 0.82 | ALDH1A1 (0.42) | MEN1NPC1KMT2ACYP2C19CPB2 | |
| SCHEMBL4056303 | 0.79 | ALDH1A1 (0.39) | MEN1NPC1KMT2ACPB2ALDH1A1 | |
| SCHEMBL26113751 | 0.77 | ALDH1A1 (0.37) | MEN1NPC1KMT2ACYP2C19CPB2 | |
| SCHEMBL19838298 | 0.76 | CPA1 (0.42) | CPA1MEN1NPC1KMT2ACYP2C19 | |
| SCHEMBL16063917 | 0.76 | HDAC1 (0.41) | MEN1NPC1KMT2ACYP2C19CPB2 | |
| SCHEMBL28091205 | 0.76 | HDAC1 (0.41) | MEN1NPC1KMT2ACYP2C19CPB2 | |
| SCHEMBL19853046 | 0.75 | CPA1 (0.41) | CPA1MEN1NPC1KMT2ACPB2 | |
| SCHEMBL18764229 | 0.75 | CPA1 (0.49) | CPA1MEN1NPC1KMT2ACYP1A2 | |
| SCHEMBL1410076 | 0.75 | CPA1 (0.49) | CPA1MEN1NPC1KMT2ACYP1A2 | |
| SCHEMBL8582165 | 0.75 | CPA1 (0.42) | CPA1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | claimed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | claimed |
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-09-09 | — | — | US | disclosed |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2019-06-06 | — | — | US | disclosed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | disclosed |
| WO-2018025295-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276954-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | HPD, ALDH18A1, PGA5 | CPA1 404/4885MEN1 3588/4885NPC1 3580/4885 |
| US-20190169125-A1 | CONCISE PROCESS FOR PREPARING 3-PYRROLIDINE CARBOXYLIC ACID DERIVATIVES | HPD, ALDH18A1, PGA5 | CPA1 404/4885MEN1 3588/4885NPC1 3580/4885 |
| US-10988446-B2 | Concise process for preparing 3-pyrrolidine carboxylic acid derivatives | HPD, ALDH18A1, PGA5 | CPA1 404/4885MEN1 3588/4885NPC1 3580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.