Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197152 | 0.72 | MLYCD (0.38) | — | |
| SCHEMBL25095584 | 0.71 | — | — | |
| SCHEMBL135270 | 0.69 | GAA (0.33) | CYP2C19 | |
| SCHEMBL30906970 | 0.68 | CYP2C9 (0.35) | CYP2C9CYP2C19 | |
| SCHEMBL13103601 | 0.66 | CA12 (0.41) | — | |
| SCHEMBL31475331 | 0.66 | REN (0.33) | — | |
| SCHEMBL13045706 | 0.65 | GABRR1 (0.34) | — | |
| SCHEMBL12353471 | 0.65 | GABRR1 (0.34) | — | |
| SCHEMBL14391167 | 0.65 | CYP2C19 (0.38) | CYP2C9CYP2C19 | |
| SCHEMBL12155646 | 0.64 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026792-A1 | SPIRO-LACTAM AND BIS-SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |