Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13119669 | 0.82 | OPRM1 (0.38) | GAAKDM4ETSHRALDH1A1ALDH2 | |
| SCHEMBL25509805 | 0.78 | CHRNB2 (0.32) | TSHRMEN1GLACYP2C19KMT2A | |
| SCHEMBL9170356 | 0.78 | ALDH1A1 (0.37) | TSHRALDH1A1ALDH2LMNAMEN1 | |
| SCHEMBL12444629 | 0.78 | LMNA (0.38) | TSHRALDH1A1ALDH2LMNAMEN1 | |
| SCHEMBL1834147 | 0.78 | PAOX (0.34) | TSHRALDH1A1ALDH2LMNAMEN1 | |
| SCHEMBL13332903 | 0.77 | CA12 (0.44) | GAAKDM4ETSHRALDH1A1LMNA | |
| SCHEMBL3200366 | 0.76 | LMNA (0.42) | GAAKDM4ETSHRALDH1A1LMNA | |
| SCHEMBL13039193 | 0.75 | MLYCD (0.37) | GAAKDM4ETSHRALDH1A1ALDH2 | |
| SCHEMBL12156217 | 0.75 | ALDH1A1 (0.43) | GAAKDM4ETSHRALDH1A1ALDH2 | |
| SCHEMBL24370669 | 0.74 | CA1 (0.35) | GAAKDM4ETSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058084-A1 | Interferon Alpha Carrier Prodrugs | ASCENDIS PHARMA AS (DK) | 2012-03-08 | — | — | US | disclosed |
| EP-2403537-A1 | INTERFERON ALPHA CARRIER PRODRUGS | Ascendis Pharma A/S (DK) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100220-A1 | INTERFERON ALPHA CARRIER PRODRUGS | ASCENDIS PHARMA AS (DK) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058084-A1 | Interferon Alpha Carrier Prodrugs | IFNG, IFNAR1, IRF3 | GAA 134/4885KDM4E 4661/4885TSHR 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.