Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30003276 | 0.77 | ACHE (0.62) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL11149087 | 0.77 | ACHE (0.62) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL2019633 | 0.69 | ACHE (0.52) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL13380161 | 0.68 | ACHE (0.56) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL17013396 | 0.67 | L3MBTL1 (0.49) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL19303605 | 0.67 | ACHE (0.48) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL15424071 | 0.67 | ACHE (0.62) | ACHEALDH1A1CYP3A4MAPTGAA | |
| SCHEMBL23458335 | 0.66 | ALDH1A1 (0.52) | ACHEALDH1A1CYP3A4MAPTLMNA | |
| SCHEMBL29862194 | 0.66 | ALDH1A1 (0.52) | ACHEALDH1A1CYP3A4MAPTLMNA | |
| SCHEMBL17188735 | 0.66 | ACHE (0.42) | ACHEALDH1A1CYP3A4MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018025259-A1 | ENZYME INHIBITORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2018-02-08 | — | — | WO | disclosed |