Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134730 | 0.82 | PIK3CA (0.42) | KMT2AOPRD1HRH3P2RX7ME2 | |
| SCHEMBL18790062 | 0.76 | CA2 (0.45) | OPRD1ALDH1A1OPRK1 | |
| SCHEMBL29139337 | 0.76 | PIK3CA (0.42) | OPRD1HRH3PPARGME2ME1 | |
| SCHEMBL19465686 | 0.72 | P2RX7 (0.44) | KMT2AOPRD1HRH3P2RX7ME2 | |
| SCHEMBL18353923 | 0.72 | SMN1; SMN2 (0.41) | HRH3KDM4EALDH1A1 | |
| SCHEMBL10068094 | 0.72 | CHRM2 (0.33) | ALDH1A1 | |
| SCHEMBL13939981 | 0.72 | KMT2A (0.44) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL18538124 | 0.72 | BRD4 (0.33) | — | |
| SCHEMBL13940081 | 0.71 | FAAH (0.34) | KMT2AHRH3KDM4EALDH1A1 | |
| SCHEMBL23071802 | 0.71 | BRD4 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428323-B2 | Reagents and methods for esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180037881-A1 | Reagents and Methods for Esterification | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428323-B2 | Reagents and methods for esterification | VIP, BCR, TMPO | KMT2A 4430/4885OPRD1 3642/4885HRH3 523/4885 |
| US-20180037881-A1 | Reagents and Methods for Esterification | VIP, BCR, TMPO | KMT2A 4430/4885OPRD1 3642/4885HRH3 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.