Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7276851 | 0.98 | TSHR (0.55) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9112270 | 0.89 | LTA4H (0.57) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL1333160 | 0.89 | KCNA3 (0.52) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL373667 | 0.83 | OPRM1 (0.48) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13406737 | 0.83 | ABCB1 (0.56) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL479112 | 0.81 | OPRM1 (0.47) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL144177 | 0.81 | OPRM1 (0.50) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL8961491 | 0.81 | OPRM1 (0.47) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9504529 | 0.81 | MEN1 (0.48) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL6566740 | 0.80 | KCNA3 (0.56) | TSHRSMN1; SMN2ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10722479-B2 | Dimethoxyphenyl inhibitors of vesicular monoamine transporter 2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20180036260-A1 | DIMETHOXYPHENYL INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | AUSPEX PHARMACEUTICALS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10722479-B2 | Dimethoxyphenyl inhibitors of vesicular monoamine transporter 2 | SLC18A2, SLC6A2, SLC6A3 | TSHR 1860/4885SMN1; SMN2 2076/4885ALDH1A1 968/4885 |
| US-20180036260-A1 | DIMETHOXYPHENYL INHIBITORS OF VESICULAR MONOAMINE TRANSPORTER 2 | SLC18A2, SLC6A2, SLC6A3 | TSHR 1860/4885SMN1; SMN2 2076/4885ALDH1A1 968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.