Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034922 | 0.82 | OPRK1 (0.35) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19853787 | 0.81 | BLM (0.35) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19853794 | 0.79 | APEX1 (0.35) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19854301 | 0.77 | OPRK1 (0.30) | APEX1BLM | |
| SCHEMBL19853729 | 0.77 | — | — | |
| SCHEMBL19854298 | 0.77 | OPRM1 (0.34) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19839384 | 0.77 | BLM (0.39) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19853789 | 0.75 | APEX1 (0.47) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL19853769 | 0.72 | TSHR (0.44) | APEX1BLMOPRM1OPRL1TSHR | |
| SCHEMBL21034514 | 0.69 | PKM (0.36) | APEX1BLMOPRM1OPRL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026763-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |