SCHEMBL19856054

SCHEMBL19856054

C=CCCC1CCC(C2CCC(c3ccc(NC(=O)C=C)cc3)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 14/20 0.42
▸ F13A1 P00488 5/20 0.41
▸ TGM1 P22735 5/20 0.41
▸ LMNA P02545 2/20 0.41
▸ TGM3 Q08188 1/20 0.41
▸ CCNK O75909 2/20 0.41
▸ CDK12 Q9NYV4 2/20 0.41
▸ IDO1 P14902 1/20 0.39
▸ HDAC3 O15379 1/20 0.39
▸ HDAC11 Q96DB2 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ HDAC6 Q9UBN7 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370539 0.85 THRA (0.51) TGM2F13A1TGM1LMNATGM3
SCHEMBL19856059 0.85 THRA (0.51) TGM2F13A1TGM1LMNATGM3
SCHEMBL19856053 0.85 ALDH1A1 (0.39) LMNAIDO1HDAC3HDAC11HDAC8
SCHEMBL19856015 0.84 TGM2 (0.43) TGM2F13A1TGM1LMNATGM3
SCHEMBL19856058 0.84 THRA (0.53) TGM2F13A1TGM1LMNATGM3
SCHEMBL19856070 0.84 THRA (0.53) TGM2F13A1TGM1LMNATGM3
SCHEMBL19854489 0.84 LMNA (0.56) TGM2F13A1TGM1LMNATGM3
SCHEMBL19854486 0.81 THRA (0.54) TGM2F13A1TGM1LMNATGM3
SCHEMBL20370605 0.80 THRA (0.46) TGM2F13A1TGM1LMNATGM3
SCHEMBL19854487 0.80 THRA (0.56) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 TGM2 4006/4885F13A1 3288/4885TGM1 3623/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 TGM2 4006/4885F13A1 3288/4885TGM1 3623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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