Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18655432 | 1.00 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A | |
| SCHEMBL20185942 | 0.96 | KMT2A (0.44) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A | |
| SCHEMBL20185941 | 0.96 | KMT2A (0.44) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A | |
| SCHEMBL28193701 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A | |
| SCHEMBL29849080 | 0.85 | MAPT (0.51) | ALDH1A1KMT2ATDP1MEN1 | |
| SCHEMBL12035649 | 0.81 | KMT2A (0.49) | ALDH1A1SMN1; SMN2HTTKMT2AGLA | |
| SCHEMBL22164503 | 0.80 | MAPT (0.47) | ALDH1A1KMT2ATDP1MEN1 | |
| SCHEMBL22164501 | 0.80 | MAPT (0.47) | ALDH1A1KMT2ATDP1MEN1 | |
| SCHEMBL29879227 | 0.80 | TBXAS1 (0.51) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A | |
| SCHEMBL29136751 | 0.80 | TBXAS1 (0.51) | ALDH1A1SMN1; SMN2HTTTSPOKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108619141-B | Antibacterial composition and application thereof | 山东轩竹医药科技有限公司 | 2021-09-10 | — | — | CN | disclosed |
| CN-108778270-B | Antibacterial composition and application thereof | 吉林四环制药有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-107531709-B | Beta-lactamase inhibitor and use thereof | 吉林四环制药有限公司 | 2020-10-23 | — | — | CN | disclosed |
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | SUANZHU PHARMA CO., LTD. (CN) | 2019-01-01 | — | — | US | disclosed |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-05-31 | — | — | US | disclosed |
| EP-3281942-A1 | B-LACTAMASE INHIBITOR AND APPLICATION THEREOF | Xuanzhu Pharma Co., Ltd. (CN) | 2018-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167283-B2 | β-lactamase inhibitors and uses thereof | MGAM, LCT, ALPI | ALDH1A1 269/4885SMN1; SMN2 1461/4885HTT 4825/4885 |
| US-20180148448-A1 | ß-LACTAMASE INHIBITORS AND USES THEREOF | MGAM, LCT, ALPI | ALDH1A1 257/4885SMN1; SMN2 1429/4885HTT 4819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.