Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22164503 | 0.95 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL22164501 | 0.95 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL22165581 | 0.91 | MAPT (0.46) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL22165582 | 0.91 | MAPT (0.46) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8173102 | 0.87 | MAPT (0.41) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL27311606 | 0.85 | RAB9A (0.44) | MAPTPOLBRAB9ATDP1MEN1 | |
| SCHEMBL18655432 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL19856430 | 0.85 | ALDH1A1 (0.46) | ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL17153016 | 0.83 | MAPT (0.41) | MAPTALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL20185942 | 0.81 | KMT2A (0.44) | MAPTALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366518-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | LIFE EDIT THERAPEUTICS, INC. | 2024-11-07 | — | — | US | disclosed |
| US-20240173267-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| EP-4291201-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | Oncorus, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022173531-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2022173531-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | ONCORUS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240173267-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | POLRMT, POLN, NSUN2 | MAPT 2349/4885ALDH1A1 4459/4885LMNA 303/4885 |
| US-20240366518-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | POLRMT, POLN, NSUN2 | MAPT 2349/4885ALDH1A1 4459/4885LMNA 303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.