SCHEMBL19856512

SCHEMBL19856512

CC(=O)OC(CCCCCN(C)C)N(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
TRPV1 Q8NER1 1/20 0.38
PAOX Q6QHF9 1/20 0.35
USP2 O75604 1/20 0.35
DNM1 Q05193 3/20 0.34
KDM4A O75164 12/20 0.34
KDM4C Q9H3R0 12/20 0.34
KDM5A P29375 1/20 0.34
KDM7A Q6ZMT4 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
KDM2A Q9Y2K7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7710315 0.84 FAAH (0.42)
SCHEMBL9128093 0.84 FAAH (0.42)
SCHEMBL7707564 0.81 FAAH (0.40) ALDH1A1
SCHEMBL19856505 0.80 TSHR (0.34) ALDH1A1TSHRDNM1KDM4AKDM4C
SCHEMBL28669002 0.79 ALDH1A1 (0.39) ALDH1A1TSHRTRPV1
SCHEMBL8495229 0.77 TSHR (0.36) TSHRTRPV1
SCHEMBL6517414 0.75 TSHR (0.37) ALDH1A1TSHRTRPV1
SCHEMBL26315 0.70 TSHR (0.40) ALDH1A1TSHRUSP2
SCHEMBL20179472 0.69 ALDH1A1 (0.40) ALDH1A1TSHRPAOXUSP2DNM1
SCHEMBL19545894 0.69 ALDH1A1 (0.40) ALDH1A1TSHRPAOXUSP2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281933-B1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2020-08-19 EP disclosed
US-10266476-B2 (Meth)acrylate manufacturing method TOAGOSEI CO., LTD. (JP) 2019-04-23 US disclosed
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO., LTD. (JP) 2018-05-03 US disclosed
EP-3281933-A1 (METH)ACRYLATE MANUFACTURING METHOD Toagosei Co., Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD MMAB, PAM, MAT2B ALDH1A1 264/4885TSHR 1174/4885TRPV1 4545/4885
US-10266476-B2 (Meth)acrylate manufacturing method MMAB, PAM, MAT2B ALDH1A1 264/4885TSHR 1174/4885TRPV1 4545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.