Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 12/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19545894 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL17178023 | 0.94 | PAOX (0.36) | ALDH1A1TSHRPAOXUSP2DNM1 | |
| SCHEMBL11226698 | 0.83 | ALDH1A1 (0.40) | ALDH1A1TSHRDNM1KDM4AKDM4C | |
| SCHEMBL21016297 | 0.81 | GPR84 (0.42) | — | |
| SCHEMBL17642018 | 0.79 | CPB2 (0.43) | PAOX | |
| SCHEMBL13930214 | 0.79 | CPB2 (0.43) | PAOX | |
| SCHEMBL6871815 | 0.79 | GPR84 (0.45) | — | |
| SCHEMBL18031703 | 0.78 | CA2 (0.40) | ALDH1A1 | |
| SCHEMBL19230435 | 0.78 | CA2 (0.40) | ALDH1A1 | |
| SCHEMBL15132427 | 0.78 | CA2 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093695-A1 | FACTOR XIIa INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2018-05-24 | — | — | WO | disclosed |