Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | UBE2M | P61081 | 6/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL841519 | 0.99 | PTPN1 (0.37) | PTPN1UBE2MDCUN1D1PPARGNR2E3 | |
| SCHEMBL1981677 | 0.94 | SMN1; SMN2 (0.39) | UBE2MDCUN1D1PPARGNR2E3NCOR2 | |
| SCHEMBL1980450 | 0.90 | UBE2M (0.39) | UBE2MDCUN1D1ALDH1A1LMNATHRB | |
| SCHEMBL1981271 | 0.89 | PPARG (0.43) | PTPN1UBE2MDCUN1D1PPARGHTT | |
| Hydrochloric Acid SCHEMBL843045 | 0.89 | UBE2M (0.38) | UBE2MDCUN1D1ALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL842280 | 0.89 | PPARG (0.43) | PTPN1UBE2MDCUN1D1PPARGHTT | |
| SCHEMBL841754 | 0.88 | KCNH2 (0.44) | UBE2MDCUN1D1ALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL842367 | 0.87 | KCNH2 (0.43) | UBE2MDCUN1D1THRB | |
| SCHEMBL1448587 | 0.86 | CCR5 (0.41) | UBE2MDCUN1D1ALDH1A1LMNAPTBP1 | |
| SCHEMBL30227264 | 0.86 | CCR5 (0.41) | UBE2MDCUN1D1ALDH1A1LMNAPTBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085275-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-04-04 | — | — | US | claimed |
| EP-2546234-A1 | Nitrogeneous heterocyclic derivative and medicine containing the same as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-01-16 | — | — | EP | claimed |
| US-20110152520-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152520-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | CXCR3, CCR5, CCR1 | PTPN1 950/4885UBE2M 4238/4885DCUN1D1 3589/4885 |
| US-20130085275-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVE AND MEDICINE CONTAINING THE SAME AS AN ACTIVE INGREDIENT | CXCR3, CCR5, CCR1 | PTPN1 950/4885UBE2M 4238/4885DCUN1D1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.