Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.38 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856872 | 1.00 | DRD2 (0.41) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856883 | 0.94 | ALOX15 (0.42) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856882 | 0.94 | ALOX15 (0.42) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856942 | 0.93 | DRD2 (0.42) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856943 | 0.93 | DRD2 (0.42) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856916 | 0.91 | CYP51A1 (0.40) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856914 | 0.91 | CYP51A1 (0.40) | DRD2STAT6ALOX15CYP51A1PYGL | |
| SCHEMBL19856897 | 0.91 | DRD2 (0.41) | DRD2STAT6CYP51A1PYGLPDGFRB | |
| SCHEMBL19856899 | 0.91 | DRD2 (0.41) | DRD2STAT6CYP51A1PYGLPDGFRB | |
| SCHEMBL1549906 | 0.91 | DRD2 (0.42) | DRD2STAT6ALOX15CYP51A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |