Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.40 |
| ▸ | PYGL | P06737 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856916 | 1.00 | CYP51A1 (0.40) | CYP51A1PYGLDRD2STAT6CCKBR | |
| SCHEMBL1549871 | 0.94 | CYP51A1 (0.40) | CYP51A1PYGLDRD2STAT6CCKBR | |
| SCHEMBL19856882 | 0.92 | ALOX15 (0.42) | CYP51A1PYGLDRD2STAT6ALOX15 | |
| SCHEMBL19856883 | 0.92 | ALOX15 (0.42) | CYP51A1PYGLDRD2STAT6ALOX15 | |
| SCHEMBL19856871 | 0.91 | DRD2 (0.41) | CYP51A1PYGLDRD2STAT6TAS1R3 | |
| SCHEMBL19856872 | 0.91 | DRD2 (0.41) | CYP51A1PYGLDRD2STAT6TAS1R3 | |
| SCHEMBL19856942 | 0.90 | DRD2 (0.42) | CYP51A1PYGLDRD2STAT6TAS1R3 | |
| SCHEMBL19856943 | 0.90 | DRD2 (0.42) | CYP51A1PYGLDRD2STAT6TAS1R3 | |
| SCHEMBL19856921 | 0.89 | CYP51A1 (0.43) | CYP51A1PYGLDRD2STAT6CCKBR | |
| SCHEMBL19856919 | 0.89 | CYP51A1 (0.43) | CYP51A1PYGLDRD2STAT6CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |