Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337973 | 0.83 | AOC3 (0.48) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL15274492 | 0.82 | L3MBTL1 (0.46) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL20365848 | 0.82 | L3MBTL1 (0.46) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL5145798 | 0.81 | CA1 (0.52) | ACHESMN1; SMN2MAOB | |
| SCHEMBL9663965 | 0.81 | NQO1 (0.67) | NPC1RAB9ASMN1; SMN2MAPTRELA | |
| SCHEMBL472078 | 0.79 | CA12 (0.53) | DRD2DRD4DRD3WDR5ACHE | |
| SCHEMBL4174011 | 0.79 | MAOB (0.42) | DRD2DRD4DRD3KCNH2MAOB | |
| SCHEMBL21811086 | 0.79 | LTA4H (0.52) | — | |
| SCHEMBL28931566 | 0.79 | ALDH1A1 (0.43) | DRD2DRD4DRD3MAPTNQO1 | |
| SCHEMBL8377414 | 0.79 | TDP1 (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057462-A1 | Substituted 2-difluoromethyl-nicotin(thio)carboxanilide derivatives and their use as fungicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-01 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-5180792-A | AMINE-CURED EPOXY RESIN WITH PHENOXYETHYL (METH) ACRYLATES | KOEI CHEMICAL CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5090994-A | HETEROCYCLIC COMPOUNDS AND HERBICIDAL COMPOSITIONS CONTAINING THE COMPOUNDS AS EFFECTIVE COMPONENTS | AGRO-KANESHO CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | DRD2 1447/4885DRD4 575/4885DRD3 675/4885 |
| US-20180057462-A1 | Substituted 2-difluoromethyl-nicotin(thio)carboxanilide derivatives and their use as fungicides | NAPRT, NAMPT, NIT2 | DRD2 604/4885DRD4 406/4885DRD3 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.