Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859936 | 0.85 | CCR1 (0.36) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL19859931 | 0.84 | TLR7 (0.38) | MEN1KMT2A | |
| SCHEMBL16582573 | 0.84 | KDM4E (0.33) | KDM4EL3MBTL1MPICOMTALDH1A1 | |
| SCHEMBL17971396 | 0.68 | MEN1 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL17971395 | 0.68 | CCR1 (0.35) | L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL16905613 | 0.65 | GABRG2 (0.36) | KDM4EL3MBTL1ALDH1A1MEN1PKM | |
| SCHEMBL16582842 | 0.63 | LMNA (0.43) | KDM4EL3MBTL1COMTALDH1A1LMNA | |
| SCHEMBL17971404 | 0.63 | GAA (0.30) | — | |
| SCHEMBL17486169 | 0.62 | KMT2A (0.34) | KDM4EL3MBTL1ALDH1A1MEN1LMNA | |
| SCHEMBL10510901 | 0.62 | SLC40A1 (0.51) | KDM4EL3MBTL1MPIALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9893299-B2 | Heterocyclic compounds | MERCK PATENT GMBH (DE) | 2018-02-13 | — | — | US | disclosed |