SCHEMBL19861020

SCHEMBL19861020

O=S(=O)(ONc1ccccc1)c1ccccc1P

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.34
CA1 P00915 4/20 0.34
KEAP1 Q14145 2/20 0.34
IL1RN P18510 1/20 0.33
ERAP1 Q9NZ08 1/20 0.33
BCAT2 O15382 1/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
PRMT1 Q99873 1/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KMT2A Q03164 2/20 0.32
PKM P14618 1/20 0.32
TTR P02766 1/20 0.31
FABP4 P15090 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960993 0.80 CHAT (0.39) CA2CA1KEAP1IL1RNERAP1
SCHEMBL7783919 0.79 POLB (0.47) CA2CA1KEAP1BCAT2MEN1
SCHEMBL9139273 0.76 PGR (0.49) CA2CA1MEN1ALDH1A1KMT2A
SCHEMBL28624207 0.76 CHAT (0.42) CA2CA1MEN1ALDH1A1KMT2A
SCHEMBL22187497 0.75 KEAP1 (0.48) CA2CA1KEAP1IL1RNERAP1
Ammonia Solution, Strong SCHEMBL28968464 0.75 PGR (0.48) CA2CA1MEN1ALDH1A1KMT2A
SCHEMBL11628679 0.73 KMT2A (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL9543035 0.72 CA2 (0.44) CA2CA1KEAP1IL1RNERAP1
SCHEMBL3226500 0.70 CA2 (0.43) CA2CA1KEAP1IL1RNERAP1
SCHEMBL9492832 0.69 KEAP1 (0.52) CA2CA1KEAP1IL1RNERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9890231-B2 Triarylphosphine or triarylarsine compound, alpha-olefin polymerization catalyst using the compound, ternary copolymer, and production process of alpha-olefin-((meth)acrylic acid)-based copolymer JAPAN POLYETHYLENE CORPORATION (JP) 2018-02-13 US disclosed