Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960993 | 0.95 | CHAT (0.39) | CHATSNCAPGRMEN1MAPT | |
| SCHEMBL9139273 | 0.87 | PGR (0.49) | PGRMEN1KMT2AALDH1A1HPGD | |
| Ammonia Solution, Strong SCHEMBL28968464 | 0.85 | PGR (0.48) | PGRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL19861020 | 0.76 | CA2 (0.34) | PGRMEN1MAPTKMT2ALMNA | |
| SCHEMBL7783919 | 0.76 | POLB (0.47) | MEN1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL22187497 | 0.72 | KEAP1 (0.48) | PGRMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11628679 | 0.71 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL10579140 | 0.70 | CA2 (0.41) | PGRMEN1MAPTKMT2ALMNA | |
| SCHEMBL28753722 | 0.70 | KEAP1 (0.49) | PGRMEN1MAPTKMT2ALMNA | |
| SCHEMBL9543035 | 0.69 | CA2 (0.44) | PGRMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227057-A | Compounds and their use for the treatment of alpha 1-antitrypsin deficiency | Z 因子有限公司 | 2021-08-06 | — | — | CN | disclosed |