Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861724 | 0.91 | ALDH1A1 (0.46) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL20053250 | 0.84 | LMNA (0.50) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL18639289 | 0.82 | LMNA (0.54) | LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL22930060 | 0.82 | LMNA (0.54) | LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL18664327 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL26976480 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL16104742 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL3884493 | 0.80 | ALDH1A1 (0.68) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL20568504 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CA2TDP1CYP3A4TSHR | |
| SCHEMBL20376061 | 0.79 | ACE2 (0.41) | ALDH1A1CA2CYP3A4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |