Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20053250 | 0.93 | LMNA (0.50) | ALDH1A1LMNAFDPSCES2LPAR1 | |
| SCHEMBL18639289 | 0.91 | LMNA (0.54) | LMNAFDPSCES2LPAR1LPAR3 | |
| SCHEMBL19861785 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL22930060 | 0.91 | LMNA (0.54) | LMNAFDPSCES2LPAR1LPAR3 | |
| SCHEMBL26976480 | 0.89 | ALDH1A1 (0.39) | ALDH1A1TDP1LMNACYP3A4TSHR | |
| SCHEMBL18639292 | 0.83 | LMNA (0.50) | LMNATSHRDNM1FDPSCES2 | |
| SCHEMBL20376061 | 0.83 | ACE2 (0.41) | ALDH1A1LMNACYP3A4TSHRCA2 | |
| SCHEMBL1678825 | 0.81 | FDPS (0.37) | CA2FDPSCES2LPAR1LPAR3 | |
| SCHEMBL4292096 | 0.81 | ALDH1A1 (0.33) | ALDH1A1TSHRCA2DNM1FDPS | |
| SCHEMBL26976460 | 0.79 | ALDH1A1 (0.32) | ALDH1A1CA2DNM1FDPSCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |