Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930060 | 0.98 | LMNA (0.54) | LMNAMAPTCES2LPAR1LPAR3 | |
| SCHEMBL18639289 | 0.98 | LMNA (0.54) | LMNAMAPTCES2LPAR1LPAR3 | |
| SCHEMBL19861724 | 0.93 | ALDH1A1 (0.46) | LMNAALDH1A1CES2LPAR1LPAR3 | |
| SCHEMBL18639292 | 0.91 | LMNA (0.50) | LMNAMAPTCES2LPAR1LPAR3 | |
| SCHEMBL19861785 | 0.84 | ALDH1A1 (0.54) | LMNAALDH1A1MEN1CYP1A2KMT2A | |
| SCHEMBL26976480 | 0.83 | ALDH1A1 (0.39) | LMNAALDH1A1CES1MEN1CYP1A2 | |
| SCHEMBL5451661 | 0.79 | — | — | |
| SCHEMBL61375 | 0.79 | — | — | |
| Methyl Alcohol SCHEMBL6417567 | 0.79 | LMNA (0.65) | LMNAALDH1A1MAPTOPRM1FDPS | |
| SCHEMBL20746331 | 0.79 | LMNA (0.63) | LMNAALDH1A1OPRM1FDPSGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944638-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND US (IE) | 2018-04-17 | — | — | US | disclosed |