Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 11/20 | 0.62 |
| ▸ | TMPRSS4 | Q9NRS4 | 9/20 | 0.62 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | IKBKB | O14920 | 1/20 | 0.62 |
| ▸ | CHUK | O15111 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | FLT3 | P36888 | 1/20 | 0.62 |
| ▸ | MYLK | Q15746 | 1/20 | 0.62 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.62 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | XPO1 | O14980 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702757 | 0.94 | P2RX1 (0.67) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL19862000 | 0.90 | P2RX1 (0.61) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL6102085 | 0.88 | P2RX1 (0.65) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL19604001 | 0.88 | TMPRSS4 (0.59) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL16703449 | 0.87 | P2RX1 (0.64) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL29511638 | 0.87 | P2RX1 (0.64) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL28359923 | 0.87 | P2RX1 (0.64) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| Potassium Ion SCHEMBL29511655 | 0.86 | P2RX1 (0.62) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL28359764 | 0.85 | P2RX1 (0.61) | P2RX1TMPRSS4P2RX7P2RX4MEN1 | |
| SCHEMBL28359926 | 0.85 | P2RX1 (0.61) | P2RX1TMPRSS4P2RX7P2RX4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894055-B2 | Pharmaceutical compositions, methods of making pharmaceutical compositions, and kits comprising 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}4-chlorophenyl dihydrogen phosphate | AEROMICS, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20190307779-A1 | NOVEL FORMULATIONS | AEROMICS, INC. (US) | 2019-10-10 | — | — | US | disclosed |
| US-20180042873-A1 | NOVEL METHODS | AEROMICS, INC. (US) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042873-A1 | NOVEL METHODS | AQP4, AQP1, AQP3 | P2RX1 2332/4885TMPRSS4 2568/4885P2RX7 2547/4885 |
| US-20190307779-A1 | NOVEL FORMULATIONS | DCPS, PRCP, DCTPP1 | P2RX1 1115/4885TMPRSS4 228/4885P2RX7 778/4885 |
| US-10894055-B2 | Pharmaceutical compositions, methods of making pharmaceutical compositions, and kits comprising 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}4-chlorophenyl dihydrogen phosphate | PLCG2, DCPS, DCTPP1 | P2RX1 641/4885TMPRSS4 1279/4885P2RX7 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.