SCHEMBL19862391

SCHEMBL19862391

CC1(C)OB(c2ccc3c(c2)C=Cc2ccccc2C32c3ccccc3-c3c2ccc2oc4ccccc4c32)OC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
LPL P06858 2/20 0.32
LIPG Q9Y5X9 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862383 0.95 PRMT5 (0.32) PRMT5WDR77LPLLIPG
SCHEMBL16491908 0.89 LPL (0.35) PRMT5WDR77LPLLIPG
SCHEMBL18034326 0.88 LPL (0.34) PRMT5WDR77LPLLIPG
SCHEMBL18034436 0.88 LPL (0.34) PRMT5WDR77LPLLIPG
SCHEMBL19862393 0.87 CSF1R (0.33) PRMT5WDR77LPLLIPG
SCHEMBL18732181 0.87 LPL (0.33) PRMT5WDR77LPLLIPG
SCHEMBL18732022 0.87 LPL (0.35) PRMT5WDR77LPLLIPG
SCHEMBL25004616 0.84 LPL (0.32) PRMT5WDR77LPLLIPG
SCHEMBL19862384 0.84 PGR (0.34) PRMT5WDR77LPLLIPG
SCHEMBL19862386 0.83 PRMT5 (0.33) PRMT5WDR77LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10454039-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-10-22 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180047918-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ORC3, AOX1, RCOR3 PRMT5 1822/4885WDR77 1593/4885LPL 4815/4885
US-10454039-B2 Compound and organic electronic device using the same ORC3, AOX1, RCOR3 PRMT5 1822/4885WDR77 1593/4885LPL 4815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.