SCHEMBL19862399

SCHEMBL19862399

Cc1cc(O)cc(C)c1C[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)NC(Cc1ccccc1)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 10/20 0.52
NPY5R Q15761 8/20 0.51
NPY1R P25929 7/20 0.51
NPY2R P49146 5/20 0.51
REN P00797 1/20 0.51
CCKBR P32239 2/20 0.51
OPRM1 P35372 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862098 1.00 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL18048887 1.00 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL19862397 1.00 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL19862401 0.99 NPY4R (0.53) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL25867315 0.96 CCKBR (0.50) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL25867236 0.95 NPY4R (0.49) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL19861965 0.95 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL25867233 0.95 OPRM1 (0.55) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL22563329 0.94 NPY4R (0.49) NPY4RNPY5RNPY1RNPY2RREN
SCHEMBL24147042 0.92 NPY4R (0.51) NPY4RNPY5RNPY1RNPY2RREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210292362-A1 CRYSTALLINE SALT FORMS OF BOC-D-ARG-DMT-LYS-(BOC)-PHE-NH2 STEALTH BIOTHERAPEUTICS INC. 2021-09-23 US disclosed
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2020-04-28 US disclosed
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044378-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD NPY4R 135/4885NPY5R 246/4885NPY1R 140/4885
US-10633415-B2 Processes for preparing pharmaceutically relevant peptides ADM2, VIP, PEPD NPY4R 135/4885NPY5R 246/4885NPY1R 140/4885
US-20210292362-A1 CRYSTALLINE SALT FORMS OF BOC-D-ARG-DMT-LYS-(BOC)-PHE-NH2 MITF, PEPD, HLA-DRB1 NPY4R 1097/4885NPY5R 1624/4885NPY1R 1353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.