Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259191 | 0.96 | ALDH1A1 (0.49) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL19862466 | 0.94 | ALOX5 (0.51) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL19862467 | 0.92 | ALDH1A1 (0.58) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL14439282 | 0.91 | ALDH1A1 (0.53) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL25833973 | 0.90 | BCHE (0.49) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL8886811 | 0.90 | ALOX5 (0.52) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL19862469 | 0.89 | ALDH1A1 (0.54) | ALOX5ALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL8885275 | 0.85 | BCHE (0.52) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL133636 | 0.84 | ALDH1A1 (0.59) | ALOX5ALDH1A1MAPK1L3MBTL1CYP3A4 | |
| SCHEMBL26454315 | 0.84 | DRD2 (0.49) | ALDH1A1MAPK1L3MBTL1DRD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044280-A1 | Y-TYPE DISCRETE POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044280-A1 | Y-TYPE DISCRETE POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF | IDUA, YWHAZ, DDOST | ALOX5 3275/4885ALDH1A1 3213/4885MAPK1 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.