Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HMGCR | P04035 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846394 | 0.88 | KMT2A (0.58) | KMT2APOLBSMN1; SMN2BAZ2BBAZ2A | |
| SCHEMBL12876004 | 0.84 | GSK3B (0.58) | KMT2ASMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL9720617 | 0.82 | TPMT (0.54) | KMT2ASMN1; SMN2BAZ2BBAZ2AMEN1 | |
| SCHEMBL7821339 | 0.81 | ALDH1A1 (0.56) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL17694477 | 0.80 | HSD17B3 (0.47) | GAA | |
| SCHEMBL27915406 | 0.80 | DDR1 (0.46) | KMT2APOLBSMN1; SMN2BAZ2BBAZ2A | |
| SCHEMBL15867157 | 0.80 | PPARA (0.40) | KMT2APOLBSMN1; SMN2BAZ2BBAZ2A | |
| SCHEMBL12020820 | 0.79 | LMNA (0.48) | KMT2ASMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL6738707 | 0.79 | TPMT (0.64) | KMT2APOLBKDM4EMEN1PKM | |
| SCHEMBL11914196 | 0.79 | ALDH1A1 (0.46) | KMT2APOLBSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2018-02-15 | — | — | US | disclosed |
| US-20110053910-A1 | 2 -HETEROCYCLYLOXYBENZOYL AMINO HETEROCYCLYL COMPOUNDS AS MODULATORS OF GLUCOKINASE FOR THE TREATMENT OF TYPE 2 DIABETES | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044284-A1 | NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS | PLG, PPARG, PKLR | KMT2A 1672/4885POLB 78/4885SMN1; SMN2 4067/4885 |
| US-20110053910-A1 | 2 -HETEROCYCLYLOXYBENZOYL AMINO HETEROCYCLYL COMPOUNDS AS MODULATORS OF GLUCOKINASE FOR THE TREATMENT OF TYPE 2 DIABETES | GCK, GCKR, HK1 | KMT2A 2481/4885POLB 3374/4885SMN1; SMN2 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.