SCHEMBL846394

SCHEMBL846394

CCC(=O)c1cc(OC)cc(OC)c1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.58
POLB P06746 1/20 0.58
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
ALDH1A1 P00352 2/20 0.48
TSHR P16473 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
BAZ2B Q9UIF8 1/20 0.44
BAZ2A Q9UIF9 1/20 0.44
MEN1 O00255 1/20 0.44
PKM P14618 1/20 0.44
HMGCR P04035 1/20 0.44
RXRA P19793 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862477 0.88 KMT2A (0.47) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL27915406 0.87 DDR1 (0.46) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL28786236 0.84 F2R (0.45) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL14236191 0.84 KMT2A (0.44) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL5838889 0.83 KDM4E (0.50) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL16151849 0.82 RXRA (0.48) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL14240790 0.81 SMN1; SMN2 (0.57) KMT2APOLBKDM4ESMN1; SMN2ALDH1A1
SCHEMBL333513 0.81 GSK3B (0.66) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL10497616 0.81 KDM4E (0.49) KMT2APOLBKDM4EGAASMN1; SMN2
SCHEMBL1038708 0.80 HSD17B3 (0.50) KDM4EGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114751576-A Method for treating dialkoxybenzene production wastewater 北京惠宇乐邦环保科技有限公司 2022-07-15 CN claimed
EP-4709724-A1 ANTICONVULSIVE COMPOUNDS AND USES THEREOF Jazz Pharmaceuticals Research UK Limited (GB) 2026-03-18 EP disclosed
EP-3722276-B1 PROCESS FOR THE PRODUCTION OF PURIFIED CANNABIDIOL PURISYS LLC (US) 2025-01-08 EP disclosed
WO-2024236275-A1 ANTICONVULSIVE COMPOUNDS AND USES THEREOF JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) 2024-11-21 WO disclosed
US-11912736-B2 Diaryl trehalose compounds and uses thereof THE UNIVERSITY OF MONTANA (US) 2024-02-27 US disclosed
CN-110526854-B Alpha, beta-unsaturated ketone derivative, preparation method and application thereof as medicine 宁夏医科大学 2023-12-15 CN disclosed
CN-114751576-A Method for treating dialkoxybenzene production wastewater 北京惠宇乐邦环保科技有限公司 2022-07-15 CN disclosed
US-20210139521-A1 DIARYL TREHALOSE COMPOUNDS AND USES THEREOF THE UNIV OF MONTANA (US) 2021-05-13 US disclosed
US-20210061781-A1 PROCESS FOR THE PRODUCTION OF CANNABIDIOL AND DELTA-9-TETRAHYDROCANNABINOL NORAMCO, INC. 2021-03-04 US disclosed
US-20210061781-A1 PROCESS FOR THE PRODUCTION OF CANNABIDIOL AND DELTA-9-TETRAHYDROCANNABINOL NORAMCO, INC. 2021-03-04 US disclosed
US-4400385-A TRANQUILIZERS, HYPOTENSIVE AGENTS; DIURETICS; VISION DEFECTS PFIZER INC. (US) 1983-08-23 US disclosed
US-4380542-A ANALGESICS, TRANQUILIZERS PFIZER (US) 1983-04-19 US disclosed
US-4340737-A CNS AGENTS, HYPOTENSIVES, DIURETICS AND AGENTS FOR TREATMENT OF GLAUCOMA PFIZER INC. (US) 1982-07-20 US disclosed
US-4260764-A ANALGESICS, TRANQUILIZERS PFIZER INC. (US) 1981-04-07 US disclosed
US-4243674-A HYPOTENSIVE AGENTS; ANALGESICS; ANTISECRETORY AGENTS; ANTIBODY INHIBITORS, AND TRANQUILIZERS PFIZER INC. (US) 1981-01-06 US disclosed
US-4143139-A ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY PFIZER INC. (US) 1979-03-06 US disclosed
US-RE29196-E ANALGESICS AND TRANQUILIZERS ABBOTT LABORATORIES (US) 1977-04-26 US disclosed
US-3947462-A 2,4,7-substituted 5-hydroxy benzopyrans and esters ABBOTT LABORATORIES (US) 1976-03-30 US disclosed
US-3932432-A Alkylphenyl benzopyranopyridines ABBOTT LABORATORIES (US) 1976-01-13 US disclosed
US-3931232-A 3-Alkyl xanthene compounds SMITHKLINE CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061781-A1 PROCESS FOR THE PRODUCTION OF CANNABIDIOL AND DELTA-9-TETRAHYDROCANNABINOL CNR2, HDHD5, DAGLA KMT2A 3227/4885POLB 988/4885KDM4E 2928/4885
US-20210139521-A1 DIARYL TREHALOSE COMPOUNDS AND USES THEREOF TREH, STT3B, DDOST KMT2A 4228/4885POLB 3142/4885KDM4E 4381/4885
US-11912736-B2 Diaryl trehalose compounds and uses thereof TREH, STT3B, DDOST KMT2A 4228/4885POLB 3142/4885KDM4E 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.