SCHEMBL19862487

SCHEMBL19862487

O=C(NC12CC3C[C@H](C1)C[C@@H](C3)C2)C(F)(F)S(=O)(=O)F

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 9/20 0.50
EPHX1 P07099 4/20 0.50
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15512063 1.00 EPHX2 (0.50) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL19863276 1.00 EPHX2 (0.50) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL10272971 0.86 EPHX2 (0.50) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL19042385 0.85 EPHX2 (0.48) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL10284312 0.81 EPHX2 (0.44) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL16604547 0.81 EPHX2 (0.44) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL7353899 0.80 EPHX2 (0.59) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL29103915 0.77 EPHX2 (0.55) EPHX2EPHX1LMNAALDH1A1KMT2A
SCHEMBL11959258 0.77 EPHX2 (0.55) EPHX2EPHX1KMT2ASMN1; SMN2MEN1
SCHEMBL15114230 0.72 EPHX2 (0.50) EPHX2EPHX1LMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9983475-B2 Fluorinated sulfonate esters of aryl ketones for non-ionic photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-05-29 US disclosed
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS PLG, PPARG, PKLR EPHX2 1386/4885EPHX1 1892/4885LMNA 910/4885
US-20180046077-A1 FLUORINATED SULFONATE ESTERS OF ARYL KETONES FOR NON-IONIC PHOTO-ACID GENERATORS PFAS, PLG, PPARG EPHX2 923/4885EPHX1 1221/4885LMNA 381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.