Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548867 | 0.82 | RAB9A (0.82) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL13548884 | 0.82 | KMT2A (0.60) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL8241328 | 0.77 | DDX3X (0.59) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL4405047 | 0.72 | KDM5A (0.52) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL13548897 | 0.71 | RAB9A (0.52) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL13548896 | 0.71 | KDM5A (0.65) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL4404326 | 0.71 | KDM5A (0.50) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL4411838 | 0.71 | KDM5A (0.65) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL19862523 | 0.70 | RAB9A (0.46) | RAB9ANPC1HTTSMN1; SMN2MITF | |
| SCHEMBL26032120 | 0.68 | RAB9A (0.52) | RAB9ANPC1HTTSMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180042935-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180042935-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | RAB9A 2031/4885NPC1 4410/4885HTT 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.