Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862712 | 0.83 | ELANE (0.54) | ELANESMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19862711 | 0.82 | ELANE (0.53) | ELANESMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19862709 | 0.80 | ELANE (0.61) | ELANESMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19862713 | 0.75 | ELANE (0.54) | ELANESMN1; SMN2ALDH1A1HTTRAB9A | |
| SCHEMBL825544 | 0.74 | ELANE (0.71) | ELANESMN1; SMN2ALDH1A1LMNAMAPK1 | |
| SCHEMBL19862715 | 0.74 | ELANE (0.43) | ELANEESR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9888810 | 0.72 | ELANE (0.43) | ELANEALDH1A1LMNAMAPK1FAAH | |
| SCHEMBL26478260 | 0.71 | ELANE (0.55) | ELANELMNACYP3A4FAAH | |
| SCHEMBL20125693 | 0.70 | ESR1 (0.66) | ESR1MLNRNR1I2NR3C1PGR | |
| SCHEMBL20125694 | 0.70 | ESR1 (0.66) | ESR1MLNRNR1I2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043066-A1 | MACROINITIATORS FOR HYDROPHILIC COATINGS ON LATEX AND APPLICATIONS THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-02-15 | — | — | US | disclosed |