Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862709 | 0.87 | ELANE (0.61) | ELANESMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19862712 | 0.81 | ELANE (0.54) | ELANESMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL825544 | 0.81 | ELANE (0.71) | ELANESMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19862711 | 0.81 | ELANE (0.53) | ELANESMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL9888810 | 0.76 | ELANE (0.43) | ELANEALDH1A1RAB9AL3MBTL1CYP1A2 | |
| SCHEMBL19862710 | 0.75 | ELANE (0.46) | ELANESMN1; SMN2ALDH1A1RAB9AHTT | |
| SCHEMBL17834010 | 0.74 | ELANE (0.54) | ELANESMN1; SMN2MEN1KMT2A | |
| SCHEMBL16406554 | 0.74 | ELANE (0.61) | ELANEALDH1A1RAB9AL3MBTL1MEN1 | |
| SCHEMBL20382904 | 0.74 | THRB (0.41) | SMN1; SMN2ALDH1A1RAB9AMEN1MAPT | |
| SCHEMBL10483728 | 0.73 | ELANE (0.62) | ELANESMN1; SMN2ALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043066-A1 | MACROINITIATORS FOR HYDROPHILIC COATINGS ON LATEX AND APPLICATIONS THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-02-15 | — | — | US | disclosed |