Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | ESRRB | O95718 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862711 | 0.83 | ELANE (0.53) | ELANESMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL19862712 | 0.80 | ELANE (0.54) | ELANESMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL19862709 | 0.77 | ELANE (0.61) | ELANESMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL19862710 | 0.74 | ELANE (0.46) | ELANEESR1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19862713 | 0.72 | ELANE (0.54) | ELANESMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL825544 | 0.71 | ELANE (0.71) | ELANESMN1; SMN2MEN1MAPTHTT | |
| SCHEMBL16406554 | 0.70 | ELANE (0.61) | ELANEESRRBMEN1KMT2AALDH1A1 | |
| SCHEMBL9888810 | 0.69 | ELANE (0.43) | ELANEMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL17834010 | 0.68 | ELANE (0.54) | ELANEESRRBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL26311013 | 0.67 | ATM (0.39) | ELANESMN1; SMN2MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043066-A1 | MACROINITIATORS FOR HYDROPHILIC COATINGS ON LATEX AND APPLICATIONS THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-02-15 | — | — | US | disclosed |