Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862712 | 0.90 | ELANE (0.54) | ELANEALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19862709 | 0.86 | ELANE (0.61) | ELANEALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19862715 | 0.83 | ELANE (0.43) | ELANEALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19862710 | 0.82 | ELANE (0.46) | ELANEALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19862713 | 0.81 | ELANE (0.54) | ELANEALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL825544 | 0.80 | ELANE (0.71) | ELANEALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9888810 | 0.77 | ELANE (0.43) | ELANEALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL17834010 | 0.76 | ELANE (0.54) | ELANESMN1; SMN2KMT2AMEN1PTGS2 | |
| SCHEMBL19862714 | 0.75 | ELANE (0.41) | ELANEALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL19498782 | 0.74 | CA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180043066-A1 | MACROINITIATORS FOR HYDROPHILIC COATINGS ON LATEX AND APPLICATIONS THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-02-15 | — | — | US | disclosed |