Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.69 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 1/20 | 0.55 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876809 | 1.00 | ALDH1A1 (0.70) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL30651167 | 1.00 | ALDH1A1 (0.70) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL30652068 | 0.99 | ALDH1A1 (0.72) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL25700291 | 0.99 | ALDH1A1 (0.72) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL29935660 | 0.99 | ALDH1A1 (0.72) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31616183 | 0.99 | ALDH1A1 (0.72) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL30649867 | 0.99 | ALDH1A1 (0.72) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL30536890 | 0.98 | ALDH1A1 (0.73) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL31615955 | 0.97 | ALDH1A1 (0.75) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT | |
| SCHEMBL30652751 | 0.97 | ALDH1A1 (0.75) | ALDH1A1NR5A2NR5A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858888-B2 | Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2024-01-02 | — | — | US | disclosed |
| US-11684599-B2 | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use | BOARD OF SUPERVISORS OF LOUSIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2023-06-27 | — | — | US | disclosed |
| US-20180044278-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF INFLAMMATORY, DEGENERATIVE, AND NEURODEGENERATIVE DISEASES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11684599-B2 | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use | ELOVL3, ELOVL1, ELOVL5 | ALDH1A1 343/4885NR5A2 1151/4885NR5A1 923/4885 |
| US-20180044278-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF INFLAMMATORY, DEGENERATIVE, AND NEURODEGENERATIVE DISEASES | PSEN2, PSEN1, ELOVL6 | ALDH1A1 1119/4885NR5A2 2022/4885NR5A1 2454/4885 |
| US-11858888-B2 | Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases | PSEN2, PSEN1, ELOVL6 | ALDH1A1 1119/4885NR5A2 2022/4885NR5A1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.