Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25699413 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL21710001 | 0.86 | ACHE (0.38) | ALDH1A1MAPTLMNASMN1; SMN2MAPK1 | |
| SCHEMBL16954278 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1990091 | 0.82 | ACHE (0.56) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL14345864 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6876872 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL3412443 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10052629 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| Ammonia Solution, Strong SCHEMBL19664447 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL16952605 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| WO-2013137479-A1 | DECAHYDROQUINOXALINE DERIVATIVES AND ANALOGS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-09-19 | — | — | WO | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | ALDH1A1 2719/4885MEN1 1882/4885KMT2A 979/4885 |
| US-20140018377-A1 | Aminopropenoates as Fungicides | ACMSD, AASDHPPT, AAAS | ALDH1A1 3199/4885MEN1 2379/4885KMT2A 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.