Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365524 | 0.77 | MEN1 (0.48) | MEN1RAB9AGFERKMT2AALOX5 | |
| SCHEMBL16775802 | 0.73 | SMN1; SMN2 (0.36) | MEN1RAB9AGFERKMT2AALOX5 | |
| SCHEMBL1810290 | 0.64 | ITGB3 (0.39) | — | |
| SCHEMBL29858005 | 0.63 | HTR3E (0.32) | — | |
| SCHEMBL18995627 | 0.61 | NOTUM (0.35) | MEN1KMT2AALOX5 | |
| SCHEMBL21273854 | 0.59 | F7 (0.38) | ALOX5 | |
| SCHEMBL19365669 | 0.57 | HTR3E (0.31) | MEN1KMT2A | |
| SCHEMBL16237549 | 0.56 | HTR3E (0.37) | MEN1KMT2A | |
| SCHEMBL23860863 | 0.56 | ALDH1A1 (0.40) | ALOX5 | |
| SCHEMBL29364018 | 0.56 | ALDH1A1 (0.40) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044338-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044338-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | SIRT1, SIRT3, SIRT2 | MEN1 3505/4885RAB9A 1244/4885GFER 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.