Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19865454 | 0.82 | EPAS1 (0.44) | EPAS1 | |
| SCHEMBL19865268 | 0.82 | EPAS1 (0.33) | EPAS1 | |
| SCHEMBL19865197 | 0.79 | CA1 (0.36) | — | |
| SCHEMBL19865445 | 0.76 | EPAS1 (0.49) | EPAS1PTGS2 | |
| SCHEMBL19865278 | 0.74 | EPAS1 (0.34) | EPAS1 | |
| SCHEMBL19865327 | 0.71 | EPAS1 (0.35) | EPAS1PTGS2 | |
| SCHEMBL19865460 | 0.71 | — | — | |
| SCHEMBL19865442 | 0.70 | EPAS1 (0.44) | EPAS1 | |
| SCHEMBL19865425 | 0.70 | EPAS1 (0.65) | EPAS1 | |
| SCHEMBL18036903 | 0.69 | EPAS1 (0.36) | CCR2EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018031680-A1 | NOVEL COMPOUNDS, USES AND METHODS FOR THEIR PREPARATION | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2018-02-15 | — | — | WO | disclosed |