Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15894733 | 0.88 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL18030871 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL14729534 | 0.81 | TSHR (0.37) | TSHR | |
| SCHEMBL21686082 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL31122350 | 0.80 | TSHR (0.54) | TSHR | |
| SCHEMBL31122351 | 0.80 | TSHR (0.54) | TSHR | |
| SCHEMBL15894728 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL14183093 | 0.76 | ALDH1A1 (0.47) | TSHR | |
| SCHEMBL10168227 | 0.73 | ALDH1A1 (0.44) | TSHR | |
| SCHEMBL11920352 | 0.73 | TSHR (0.44) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479848-B2 | Addition-fragmentation oligomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180044448-A1 | ADDITION-FRAGMENTATION OLIGOMERS | 3M INNOVATIVE PROPERTIES COMPANY | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479848-B2 | Addition-fragmentation oligomers | ECPAS, ITGA8, NBAS | TSHR 4794/4885 |
| US-20180044448-A1 | ADDITION-FRAGMENTATION OLIGOMERS | ECPAS, ITGA8, NBAS | TSHR 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.