Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095212 | 0.83 | LPL (0.32) | LPLLIPG | |
| SCHEMBL18696943 | 0.74 | P2RX7 (0.37) | LPLLIPG | |
| SCHEMBL17449164 | 0.71 | LPL (0.32) | LPLLIPG | |
| SCHEMBL16094973 | 0.67 | PSEN1 (0.34) | LPLLIPG | |
| SCHEMBL17448814 | 0.60 | TSHR (0.31) | — | |
| SCHEMBL22683677 | 0.58 | HDAC1 (0.54) | LPLLIPG | |
| SCHEMBL15166628 | 0.58 | P2RX7 (0.34) | — | |
| SCHEMBL28467539 | 0.57 | ACHE (0.45) | — | |
| SCHEMBL27620783 | 0.57 | ACHE (0.45) | — | |
| SCHEMBL19326734 | 0.56 | P2RX7 (0.38) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970232-B1 | SUBSTITUTED PYRIDINE DERIVATIVES USEFUL AS C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-14 | — | — | EP | disclosed |