Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 6/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12309702 | 0.81 | ADORA3 (0.41) | ALDH1A1AHRHSD17B10KDM4EHPGD | |
| SCHEMBL19948493 | 0.81 | AHR (0.39) | ALDH1A1AHRHSD17B10KDM4EHPGD | |
| SCHEMBL23640656 | 0.81 | ALDH1A1 (0.32) | ALDH1A1AHRHSD17B10KDM4EHPGD | |
| SCHEMBL10291045 | 0.81 | AHR (0.39) | ALDH1A1AHRHSD17B10KDM4EHPGD | |
| SCHEMBL20326294 | 0.78 | NR3C1 (0.32) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL12309699 | 0.78 | BRD4 (0.41) | ALDH1A1KDM4EPOLBKMT2ARHEB | |
| SCHEMBL14752560 | 0.78 | HSD17B10 (0.31) | ALDH1A1HSD17B10KDM4EHPGDGLA | |
| SCHEMBL23088298 | 0.77 | IMPDH2 (0.37) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL29792643 | 0.77 | CFB (0.35) | ALDH1A1RHEBP2RX7DHFR | |
| SCHEMBL23088075 | 0.77 | CFB (0.35) | ALDH1A1RHEBP2RX7DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045724-B | Phosphonic acid water reducing agent containing indole skeleton structure, and preparation method and application thereof | 江苏苏博特新材料股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-113045724-A | Phosphonic acid water reducing agent containing indole skeleton structure, and preparation method and application thereof | 江苏苏博特新材料股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-113045724-B | Phosphonic acid water reducing agent containing indole skeleton structure, and preparation method and application thereof | 江苏苏博特新材料股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3558955-B1 | BENZISOTHIAZOLE, ISOTHIAZOLO[3,4-B]PYRIDINE, QUINAZOLINE, PHTHALAZINE, PYRIDO[2,3-D]PYRIDAZINE AND PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS KRAS G12C INHIBITORS FOR TREATING LUNG, PANCREATIC OR COLORECTAL CANCER | AMGEN INC (US) | 2021-08-11 | — | — | EP | disclosed |
| WO-2021139678-A1 | PYRIDOPYRIMIDINE KRAS G12C MUTANT PROTEIN INHIBITOR | 广州百霆医药科技有限公司 | 2021-07-15 | — | — | WO | disclosed |
| CN-113045724-A | Phosphonic acid water reducing agent containing indole skeleton structure, and preparation method and application thereof | 江苏苏博特新材料股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| WO-2021063346-A1 | KRAS G12C INHIBITOR AND APPLICATION THEREOF | 上海迪诺医药科技有限公司 | 2021-04-08 | — | — | WO | disclosed |
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044291-A1 | ARTIFICIAL SELF-SUFFICIENT CYTOCHROME P450S | CYP4F2, POR, CYP4F3 | ALDH1A1 449/4885AHR 842/4885HSD17B10 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.