Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859913 | 0.85 | NFE2L2 (0.47) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL30305710 | 0.82 | KDM4E (0.44) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL26674983 | 0.82 | KDM4E (0.44) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL286833 | 0.78 | KDM4E (0.55) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL5325529 | 0.78 | CTNNB1 (0.46) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL11919358 | 0.78 | NFE2L2 (0.45) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL3058112 | 0.77 | KDM4E (0.53) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL1570557 | 0.77 | CTNNB1 (0.45) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL3058108 | 0.77 | CTNNB1 (0.45) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A | |
| SCHEMBL17984755 | 0.77 | CNR2 (0.41) | NFE2L2HCRTR1HCRTR2CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | NFE2L2 3979/4885HCRTR1 4003/4885HCRTR2 4536/4885 |
| US-20140018377-A1 | Aminopropenoates as Fungicides | ACMSD, AASDHPPT, AAAS | NFE2L2 3719/4885HCRTR1 4460/4885HCRTR2 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.