Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035440 | 0.90 | PPIB (0.49) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL12643833 | 0.80 | PPIB (0.46) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL19882131 | 0.80 | PPIB (0.53) | MEN1KMT2AHTTPPIDL3MBTL1 | |
| SCHEMBL19882147 | 0.79 | TSPO (0.53) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL2037947 | 0.76 | PPIB (0.62) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL2041992 | 0.71 | PPIB (0.51) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL12643831 | 0.71 | PPIB (0.51) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL2040991 | 0.68 | PPIB (0.69) | ALDH1A1MEN1KMT2AHTTPPID | |
| SCHEMBL334398 | 0.68 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL2038255 | 0.67 | PPIB (0.58) | ALDH1A1MEN1KMT2AHTTPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |