Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882131 | 0.89 | PPIB (0.53) | TSPOSMN1; SMN2ROCK2MEN1KMT2A | |
| SCHEMBL2038255 | 0.89 | PPIB (0.58) | TSPOALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12643832 | 0.80 | PPIB (0.53) | TSPOALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19882134 | 0.79 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL2040991 | 0.78 | PPIB (0.69) | TSPOALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2038459 | 0.75 | PPIB (0.54) | MEN1KMT2ALMNAGAAPPIB | |
| SCHEMBL3815151 | 0.74 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2ROCK2MEN1KMT2A | |
| SCHEMBL2034561 | 0.74 | PPIB (0.76) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2037882 | 0.73 | PPID (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL16270332 | 0.71 | MEN1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516387-B1 | INHIBITORS OF CYCLOPHILINS FOR USE IN THE PREVENTION AND/OR THE TREATMENT OF VIRAL PATHOLOGIES OR INFECTIONS | INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECH MÉDICALE (INSERM) (FR) | 2018-02-21 | — | — | EP | disclosed |