Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18029842 | 0.86 | HTR1A (0.40) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL18005335 | 0.86 | HTR1A (0.40) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL18005631 | 0.74 | HTR1A (0.40) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL18005401 | 0.70 | TSHR (0.51) | TSHRLMNAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19899742 | 0.70 | PDE10A (0.44) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL18005467 | 0.70 | PDE10A (0.44) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL29733060 | 0.70 | PDE10A (0.44) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL18005408 | 0.68 | PDE10A (0.46) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL24331778 | 0.67 | DRD2 (0.43) | DRD2HTR7HTR6HTR1AHTR2A | |
| SCHEMBL23781493 | 0.67 | CASP1 (0.44) | DRD2HTR7HTR6HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016133959-A9 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |