SCHEMBL19896448

SCHEMBL19896448

CCCC(c1ccccc1)n1c2cc(N=C(c3ccccc3)c3ccccc3)ccc2c2ccc(N=C(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 4/20 0.36
▸ OPRM1 P35372 3/20 0.36
▸ OPRK1 P41145 3/20 0.36
▸ OPRL1 P41146 3/20 0.36
▸ BRD4 O60885 1/20 0.35
▸ SLC6A2 P23975 5/20 0.33
▸ SLC6A4 P31645 3/20 0.33
▸ PDGFRB P09619 4/20 0.32
▸ KDR P35968 4/20 0.32
▸ HKDC1 Q2TB90 1/20 0.31
▸ ESR1 P03372 1/20 0.31
▸ ESR2 Q92731 1/20 0.31
▸ CYP17A1 P05093 1/20 0.31
▸ AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19896380 0.91 OPRM1 (0.40) OPRD1OPRM1OPRK1OPRL1BRD4
SCHEMBL19896310 0.91 OPRM1 (0.40) OPRD1OPRM1OPRK1OPRL1BRD4
SCHEMBL19896318 0.81 CNR2 (0.34) OPRD1BRD4PDGFRBKDRESR1
SCHEMBL19896308 0.81 BRD4 (0.38) BRD4PDGFRBKDRESR1ESR2
SCHEMBL19896281 0.75 OPRM1 (0.38) OPRD1OPRM1OPRK1OPRL1BRD4
SCHEMBL19896296 0.74 CNR2 (0.46) —
SCHEMBL19896383 0.74 MAPT (0.45) OPRD1PDGFRBKDRESR1ESR2
Hydrochloric Acid SCHEMBL19896465 0.74 KDM4E (0.40) OPRD1OPRM1OPRK1OPRL1BRD4
SCHEMBL19896356 0.72 CNR2 (0.50) —
SCHEMBL19896452 0.72 CNR2 (0.50) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 OPRD1 3087/4885OPRM1 4146/4885OPRK1 2750/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 OPRD1 3087/4885OPRM1 4146/4885OPRK1 2750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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