SCHEMBL19899151

SCHEMBL19899151

CC(=O)OC1Cc2cccc(F)c2C1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.39
AADAT Q8N5Z0 2/20 0.38
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
NOS3 P29474 2/20 0.35
NOS2 P35228 1/20 0.35
TP53 P04637 1/20 0.34
NOTUM Q6P988 2/20 0.34
DRD2 P14416 2/20 0.33
CHRM4 P08173 1/20 0.33
HTR7 P34969 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTR2A P28223 1/20 0.33
NSD2 O96028 1/20 0.33
HK1 P19367 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19899056 0.87 CHRM4 (0.41) KIF11AADATNOTUMDRD2CHRM4
SCHEMBL19899123 0.82 NOS3 (0.38) AADATMAOAMAOBNOS3TP53
SCHEMBL28526989 0.80 POLB (0.45) KIF11NOS3NOS2DRD2HTR7
SCHEMBL8605029 0.76 ACHE (0.51) TDP1
SCHEMBL943506 0.76 ACHE (0.51) TDP1
SCHEMBL17768596 0.73 KDM4E (0.36) TDP1NSD2GABRA1GABRB2
SCHEMBL28381823 0.72 ACHE (0.42) NOS3NOS2NOTUMDRD2HTR7
SCHEMBL29700470 0.70 AADAT (0.41) KIF11AADATMAOAMAOBNOS3
SCHEMBL11490469 0.70 POLB (0.50) NOTUMDRD2CHRM4HTR7GABRA1
SCHEMBL19899120 0.70 P2RX7 (0.40) TP53DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423431-B1 CARBAMATE DERIVATIVE COMPOUNDS AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2023-11-29 EP disclosed
EP-3423431-B1 CARBAMATE DERIVATIVE COMPOUNDS AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2023-11-29 EP disclosed
US-11168052-B2 Carbamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. 2021-11-09 US disclosed
US-11168052-B2 Carbamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. 2021-11-09 US disclosed
CN-109195946-B Carbamate derivative compound, preparation method and application thereof 生物药品解决方案有限公司 2021-09-07 CN disclosed
EP-3423431-A1 CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES Bio-Pharm Solutions Co., Ltd. (KR) 2019-01-09 EP disclosed
US-20180057449-A1 CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2018-03-01 US disclosed
US-20180057449-A1 CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2018-03-01 US disclosed
US-20180057449-A1 CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO-PHARM SOLUTIONS CO., LTD. (KR) 2018-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11168052-B2 Carbamate derivative compounds, processes for preparing them and their uses ACHE, BCHE, AQP4 KIF11 2898/4885AADAT 1036/4885MAOA 1692/4885
US-20180057449-A1 CARBAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES ACHE, BCHE, AQP4 KIF11 2898/4885AADAT 1036/4885MAOA 1692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.