Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL6114090 | 0.94 | F2 (0.46) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL1990018 | 0.94 | F2 (0.46) | F2PRSS1PRSS2PRSS3CA2 | |
| Potassium Ion SCHEMBL1991930 | 0.92 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA2 | |
| Lithium Ion SCHEMBL3147600 | 0.87 | F2 (0.42) | F2PRSS1PRSS2PRSS3CA2 | |
| Lithium Ion SCHEMBL6113979 | 0.86 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL8985757 | 0.86 | F2 (0.59) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL1997714 | 0.86 | F2 (0.56) | F2PRSS1PRSS2PRSS3CA2 | |
| Lithium Ion SCHEMBL1245900 | 0.80 | F2 (0.50) | F2PRSS1PRSS2PRSS3CA2 | |
| SCHEMBL242874 | 0.79 | F2 (0.38) | F2PRSS1PRSS2PRSS3CA2 | |
| Lithium Ion SCHEMBL1248473 | 0.77 | F2 (0.36) | F2PRSS1PRSS2PRSS3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005500-B2 | Method of manufacturing film for film capacitor and film for film capacitor | SHIN-ETSU POLYMER CO., LTD. (JP) | 2015-04-14 | — | — | US | claimed |
| US-20110151187-A1 | METHOD OF MANUFACTURING FILM FOR FILM CAPACITOR AND FILM FOR FILM CAPACITOR | SHIN-ETSU POLYMER CO., LTD. (JP) | 2011-06-23 | — | — | US | claimed |
| US-11090902-B2 | Pressure-sensitive adhesive composition, pressure-sensitive adhesive layer, pressure-sensitive adhesive-layer—attached polarizing film, and image display device | NITTO DENKO CORPORATION (JP) | 2021-08-17 | — | — | US | disclosed |
| US-11046045-B2 | — | — | 2021-06-29 | — | — | US | disclosed |
| EP-2597120-B1 | HIGHLY-THERMALLY-CONDUCTIVE POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY | MITSUBISHI ENG PLASTICS CORP (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-20200207058-A1 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION, PRESSURE-SENSITIVE ADHESIVE LAYER, PRESSURE-SENSITIVE ADHESIVE-LAYER-ATTACHED POLARIZING FILM, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2020-07-02 | — | — | US | disclosed |
| US-20180051188-A1 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION, PRESSURE-SENSITIVE ADHESIVE LAYER, PRESSURE-SENSITIVE ADHESIVE-LAYER-ATTACHED POLARIZING FILM, AND IMAGE DISPLAY DEVICE | NITTO DENKO CORPORATION (JP) | 2018-02-22 | — | — | US | disclosed |
| EP-2482140-B1 | Pressure roller and fixing device equipped with the same | CANON KK (JP) | 2016-11-16 | — | — | EP | disclosed |
| EP-2482141-B1 | Pressure roller and fixing device equipped with the same | CANON KK (JP) | 2016-11-09 | — | — | EP | disclosed |
| US-9005500-B2 | Method of manufacturing film for film capacitor and film for film capacitor | SHIN-ETSU POLYMER CO., LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-8886105-B2 | Pressure roller and fixing device equipped with the same | CANON KABUSHIKI KAISHA (JP) | 2014-11-11 | — | — | US | disclosed |
| EP-2597120-A1 | HIGHLY-THERMALLY-CONDUCTIVE POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY | Mitsubishi Engineering-Plastics Corporation (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20120195658-A1 | PRESSURE ROLLER AND FIXING DEVICE EQUIPPED WITH THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120195657-A1 | PRESSURE ROLLER AND FIXING DEVICE EQUIPPED WITH THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120195654-A1 | FIXING ROTATING MEMBER AND FIXING DEVICE EQUIPPED WITH THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-08-02 | — | — | US | disclosed |
| EP-2482139-A1 | Fixing rotating member and fixing device equipped with the same | Canon Kabushiki Kaisha (JP) | 2012-08-01 | — | — | EP | disclosed |
| EP-2482140-A1 | Pressure roller and fixing device equipped with the same | Canon Kabushiki Kaisha (JP) | 2012-08-01 | — | — | EP | disclosed |
| EP-2482141-A1 | Pressure roller and fixing device equipped with the same | Canon Kabushiki Kaisha (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-20120129990-A1 | HIGH-THERMAL-CONDUCTIVITY POLYCARBONATE RESIN COMPOSITION AND FORMED PRODUCT | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2012-05-24 | — | — | US | disclosed |
| US-20110151187-A1 | METHOD OF MANUFACTURING FILM FOR FILM CAPACITOR AND FILM FOR FILM CAPACITOR | SHIN-ETSU POLYMER CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |